Cheap bus tickets from Detroit, MI to Greenville, SC

Buses from Detroit to Greenville

Find the cheapest buses from Detroit to Greenville

It couldn't be easier to book your travel from Detroit to Greenville with FlixBus - and when you book in advance, you can save money too!
FlixBus operates in 45 countries connecting 5000 destinations. So no matter where you want to go, we can take you there!
To get the cheapest tickets, book online in advance and avoid busy times like weekends and public holidays.
The distance between Detroit and Greenville is 772 miles, which takes as little as 19 hours 5 minutes with our fastest rides.

Make your journey even easier with the FlixBus app. All your information will be saved for the next time you travel.

Taking the bus from Detroit

Ready for your journey from Detroit? Detroit is a transport hub with 2 stations and it is seriously well connected with buses to 79 destinations across the country.
No matter where you're traveling from, you can find plenty of information on our website or by contacting FlixBus directly for travel information. We'll do our best to make sure you're well-equipped for your journey, so you can experience everything the trip has to offer.

Arriving in Greenville

Start planning your trip to Greenville now. Never visited before? Here's all you need to know.
Greenville is one of the best-connected cities, so you're not short on choices of how to get here. 1 is the number of bus stations FlixBus has in Greenville, connecting 16 cities.
Never miss a beat as you sample the sights and culture synonymous with this famous city. Now is the time to hop aboard FlixBus and explore!

What to expect onboard the FlixBus bus from Detroit to Greenville

Traveling from Detroit to Greenville is quick, clean and comfortable - and it couldn't be easier to book a ticket. You can book online via the website, on our app, in person at a FlixShop or using Google Assistant.
We accept card payment as well as Paypal, Google Pay and Apple Pay, but there are many more payment options that you can choose from. The easiest way to book your ticket is using our app. You'll be able to make your reservation within seconds and there's no need to print and carry the ticket with you, as your phone will be your ticket.

Want to sit beside family or friends or keep the space beside you free? Need easy access to the toilet or a table to get on with some work whilst traveling? You can reserve a seat when you book on the app or website, and you can choose from a variety of seat options including a table seat, panorama seat or extra seat. Once you're settled in your seat, you can sit back and relax with plenty of onboard services to help you make the most of your trip. Most of our buses have onboard Wifi and an entertainment system so you can catch up on your favorite shows or listen to audiobooks. We've also got toilets onboard, as well as power outlets.
What's more, you get a generous luggage allowance when you travel with FlixBus with one carry-on bag and one checked bag, so you can bring everything you need for your trip.