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Cheap bus tickets from La Crosse, WI to Sioux Falls, SD

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Bus stations and stops in La Crosse, WI

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

With FlixBus, you can conveniently reach 38 destinations from Sioux Falls, including Minneapolis, Rapid City, Omaha.
The fastest bus from La Crosse to Sioux Falls takes 21 hours 25 minutes.
The bus journey from La Crosse to Sioux Falls is 770 miles. FlixBus can get you there in 21 hours 25 minutes.
When purchasing your bus ticket from La Crosse to Sioux Falls, you can choose your preferred payment method from card, Paypal, Google Pay, and more.
Our Real-Time Bus Tracker allows you to track your bus location. Just select the relevant bus stop and check the time of arrival. This way, you can find out where your bus is and check for delays on the route.
FlixBus allows you to bring your bike on board from La Crosse to Sioux Falls, subject to availability. Check out our prices for bike transport here.

Find the cheapest buses from La Crosse to Sioux Falls

Getting from La Crosse to Sioux Falls is cheap and easy when you travel with FlixBus. The two cities are 770 miles apart and traveling between the two takes as fast as 21 hours 25 minutes.
FlixBus tickets are always good value, but you can save even more money by booking online in advance. Book on the website or our FlixBus App in minutes, then simply use your phone as your ticket to board the bus.

For a quick, easy and environmentally-conscious choice, travel with FlixBus.
We have a large network of destinations, so you can trust us to take you from your desired departure city to your destination in comfort and style - all for great value.

Taking the bus from La Crosse

Traveling from La Crosse and not familiar with it? Here's everything you need to know.
La Crosse is a transport hub with 2 bus station(s); the 6 connections departing from La Crosse every day take travelers both within the state and further afield.

Arriving in Sioux Falls

Traveling to Sioux Falls for the first time? Here's what you need to know:
Sioux Falls is very well connected to other destinations on the FlixBus network, with 38 connections arriving in one of the 1 bus station(s) of the city, giving you easy access to all corners of the country.

What to expect onboard the FlixBus bus from La Crosse to Sioux Falls

Getting from La Crosse to Sioux Falls aboard a FlixBus bus means traveling in comfort and style, with all the services you need to keep you occupied. Most of our buses include free Wi-Fi onboard, an entertainment system, toilets and power outlets.
You can bring one carry-on and one check-in piece of luggage per passenger, so even if you're taking a long trip, you don't need to worry about traveling light.
All ticket holders are guaranteed a seat on our buses but if you want to reserve a seat, you can do so at the time of booking. Choose from a classic seat, table seat, panorama seat or extra seat.
Just book online or on our FlixBus App when purchasing your ticket using any of our available payment methods.

Onboard services are subject to availability