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Cheap bus tickets from Lake City, FL to Greenville, SC

from $105.99

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Bus stations and stops in Lake City, FL

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

With FlixBus, you can conveniently reach 16 destinations from Greenville, including Atlanta, Charlotte, New York.
Yes, night trip options are available from Lake City to Greenville. Check out the route's schedule and choose the best option to suit your plans!
FlixBus offers a Real-Time Bus Tracker that allows you to track your bus location. Simply select the relevant bus stop and check the time of arrival. This way, you can find out where your bus is and check for delays on the route.
You can get from Lake City to Greenville by bus in 8 hours 40 minutes.
The distance between Lake City and Greenville by bus is 440 miles. FlixBus can make the trip in 8 hours 40 minutes.
FlixBus offers a variety of payment methods for buying your bus ticket from Lake City to Greenville, including card, Paypal, Google Pay, and more.
If you want to bring your bike with you on FlixBus between Lake City and Greenville, you can. Transport options and prices are subject to availability. Check out our prices for bike transport herel .

Find the cheapest buses from Lake City to Greenville

Getting from Lake City to Greenville is cheap and easy when you travel with FlixBus. The two cities are 440 miles apart and traveling between the two takes as fast as 8 hours 40 minutes.
FlixBus tickets are always good value, but you can save even more money by booking online in advance. Book on the website or our FlixBus App in minutes, then simply use your phone as your ticket to board the bus.

For a quick, easy and environmentally-conscious choice, travel with FlixBus.
We have a large network of destinations, so you can trust us to take you from your desired departure city to your destination in comfort and style - all for great value.

Taking the bus from Lake City

Traveling from Lake City and not familiar with it? Here's everything you need to know.
Lake City is a transport hub with 1 bus station(s); the 26 connections departing from Lake City every day take travelers both within the state and further afield.

Arriving in Greenville

Traveling to Greenville for the first time? Here's what you need to know:
Greenville is very well connected to other destinations on the FlixBus network, with 16 connections arriving in one of the 1 bus station(s) of the city, giving you easy access to all corners of the country.

What to expect onboard the FlixBus bus from Lake City to Greenville

Getting from Lake City to Greenville aboard a FlixBus bus means traveling in comfort and style, with all the services you need to keep you occupied. Most of our buses include free Wi-Fi onboard, an entertainment system, toilets and power outlets.
You can bring one carry-on and one check-in piece of luggage per passenger, so even if you're taking a long trip, you don't need to worry about traveling light.
All ticket holders are guaranteed a seat on our buses but if you want to reserve a seat, you can do so at the time of booking. Choose from a classic seat, table seat, panorama seat or extra seat.
Just book online or on our FlixBus App when purchasing your ticket using any of our available payment methods.

Onboard services are subject to availability