Skip to main content

Cheap bus tickets from Wytheville, VA to San Antonio, TX

Comfort on board

Our buses are equipped with large and comfortable seats, a toilet, Wi-Fi and power outlets.
Our onboard service

Health and Safety

Keep yourself and others safe while traveling with us.
Learn more

Satisfied Customers

We've transported 100+ million happy customers worldwide. US customers give us an amazing 4.5 stars.
Read customer reviews

The Green Choice

FlixBus is one of the most eco-friendly ways to travel. Learn more about our sustainability initiatives and carbon offset programs.
Offset emissions for your trips

On this page

Bus stations and stops in Wytheville, VA

Please note: your ticket will contain the most up-to-date address information.

Discover all destinations

Choose from over 80 travel destinations in 11 states and growing!

Onboard services are subject to availability