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Cheap bus tickets from Des Moines, IA to Chicago, IL

from $46.99
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Bus stations and stops in Des Moines, IA

Please note: your ticket will contain the most up-to-date address information.

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Frequently asked questions

The cost of a bus ticket from Des Moines to Chicago starts at just $50.98.
The bus journey from Des Moines to Chicago is 361 miles. FlixBus can get you there in 6 hours 10 minutes.
Yes! There are 2 rides daily from Des Moines to Chicago.
When purchasing your bus ticket from Des Moines to Chicago, you can choose your preferred payment method from card, Paypal, Google Pay, and more.
Our Real-Time Bus Tracker allows you to track your bus location. Just select the relevant bus stop and check the time of arrival. This way, you can find out where your bus is and check for delays on the route.
Yes, night trip options are available from Des Moines to Chicago. Check out the route's schedule and choose the best option to suit your plans!
With FlixBus, you can conveniently reach 107 destinations from Chicago, including Indianapolis, Lafayette, Minneapolis.

Onboard services are subject to availability