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Cheap bus tickets from San Diego, CA to Knoxville, TN

from $298.99

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Bus stations and stops in San Diego, CA

Please note: your ticket will contain the most up-to-date address information.

Discover all destinations

Choose from over 80 travel destinations in 11 states and growing!

Frequently asked questions

With FlixBus, you can conveniently reach 23 destinations from Knoxville, including Nashville, Atlanta, Memphis.
Yes, night trip options are available from San Diego to Knoxville. Check out the route's schedule and choose the best option to suit your plans!
FlixBus offers a Real-Time Bus Tracker that allows you to track your bus location. Simply select the relevant bus stop and check the time of arrival. This way, you can find out where your bus is and check for delays on the route.
You can get from San Diego to Knoxville by bus in 56 hours 40 minutes.
The distance between San Diego and Knoxville by bus is 2488 miles. FlixBus can make the trip in 56 hours 40 minutes.
You can travel from San Diego to Knoxville for as little as $216.99.
FlixBus offers a variety of payment methods for buying your bus ticket from San Diego to Knoxville, including card, Paypal, Google Pay, and more.
FlixBus tickets start at just $216.99. You can easily book your ticket on the website or through the app. Book ahead to get the best price.
If you want to bring your bike with you on FlixBus between San Diego and Knoxville, you can. Transport options and prices are subject to availability. Check out our prices for bike transport herel .

Find the cheapest buses from San Diego to Knoxville

Looking for cheap tickets from San Diego to Knoxville? FlixBus has you covered. The distance between San Diego and Knoxville is 2488 miles, which takes a minimum of 56 hours 40 minutes.
FlixBus has a large nationwide network, so you can travel onwards with us once you reach Knoxville. Tickets for this connection cost $471.99 on average, but you can book a trip for as little as $216.99.The lowest price for this connection is $216.99, but prices might be higher during high season and when the bus gets full.
So how to find the best ticket prices? Be sure to book in advance on our website or via our FlixBus App. When booking through the App, your ticket will be stored directly, making bus travel even more green and convenient!

Taking the bus from San Diego

San Diego is well-connected on the FlixBus network with 31 connections departing every day from 6 stations, making it very easy to travel across the country.

Arriving in Knoxville

With 1 bus station(s), San Diego is well-connected. Traveling with FlixBus around the country is very cheap and easy, as to get to Knoxville you can pick one of the 23 routes arriving daily.

What to expect onboard the FlixBus bus from San Diego to Knoxville

Once you've booked your bus tickets through the FlixBus App using one of our secure payment methods, you just need to bring your phone to use as your ticket - and your luggage, of course. Don't worry about packing light as you can bring one piece of carry-on luggage and one piece of hold luggage for your journey.
Want to be guaranteed the best seat in the house? You can choose yours when you book your ticket. Opt for a classic seat, a table seat, a panorama seat for a great view, or reserve the free seat beside you for extra space.
Once you've stowed your luggage away and settled in, sit back and enjoy the journey with the onboard services on your FlixBus bus including free Wi-Fi onboard, FLIXtainment - out entertainment portal, toilets and plug socket.Whether you need to fire off some emails during your trip, or you want to relax and enjoy the ride, we've got you covered.

Onboard services are subject to availability